Thrombus

Question: Why might a thrombus in the anterior descending branch of the left coronary artery cause sudden death? Why might a thrombus in the anterior descending branch of the left coronary artery cause sudden death?

Answer: The anterior descending branch of the LCA supplies a good portion of the Left Ventricle of the heart. This chamber requires more blood flow than any of the other 3 chambers of the 4 chambered human heart. This is due to the fact that the left ventricle must pump blood through the entire systemic circulation before it returns to the right atrium/right ventricle to be sent through the pulmonary circulation (lungs). The left and right atria are less important than the ventricles in pumping blood. Because the left ventricle must generate so much more force than the right ventricle, it is much more sensitive to deoxygenation than the right ventricle. Oxygen is required for the heart muscle to "pump." Thrombus blocks the bloodflow to heart muscle cells (to a certain extent). The other way (and more likely to cause very sudden death) is through the LAD's function as blood supply to the IV septum, where cardiac pacemaker cells are. Cardiac pacemaker cells (of various types) link your atrial contractions with ventricular contractions so that the muscle contracts in a smooth, uniform, motion. Without oxygen delivery to these cells, the various parts of the heart may attempt to contract out of sequence (or maybe all at the same time), leading to the blood not actually being pumped out of the heart. It can also cause other thrombi to be released within the atrium as a result of the awkward pumping mechanism that the heart is not used to.

Question: What are the differences between atherosclerosis and thrombus? Plz state more than 3 differences.

Answer: Atherosclerosis is the name for a condition that occurs when plaques form on the inner lining of the blood vessels. It is composed of fatty material which accumulates and can become calcified. Atherosclerosis forms in muscular arteries and the aorta. When atheromatous plaques break free (embolization) they commonly go to the brain and cause an aneurysm (if the plaque was located in the carotids). They form because of elevated cholesterols (LDL, VLDL) A thrombus is the name for a blood clot that forms on the inner lining of your blood vessels-most commonly the deep legs veins. There are a number of causes, but the general cause is "blood stasis". When blood is unable to circulate (due to poor circulation, obesity, a long term hospital stay, long term immobility) it settles and forms clots. People with "hypercoagulable" states also form clots more easily that normal people. These clots can occlude a vessel can cause an infarction of tissue or an organ. If the clot breaks free (embolization), it most frequently goes to the lungs where it causes a pulmonary embolism.

Question: What factors place a person at risk for thrombus formation in leg veins? What are the major complications of venous thromb?

Answer: decreased mobility, birthcontrol user who smokes over 35, people with congestive heart failure, cancer patients, post operative patients.

Question: What is the difference between a thrombus and a thrombosis?

Answer: ones a clot and one isn't

Question: What is the difference between an embolus and a thrombus? What's the difference between the two? I'm confused

Answer: Embolus - An obstruction causing an embolism: a blood clot, air bubble or other matter carried by the blood stream and causing a blockage or occlusion of a blood vessel. An embolus occurs when an object migrates from one part of the body (through circulation) and causes a blockage (occlusion) of a blood vessel in another part of the body. This is in contrast with a thrombus, or clot, which forms at the blockage point within a blood vessel and is not carried from somewhere else. However, if a thrombus breaks loose from its location and travels to another location, it is then said to be an embolus and having caused an embolism. Thrombus - a clot of coagulated blood that forms within a blood vessel or inside the heart and remains at the site of its formation. A blood clot in a blood vessel or within the heart

Question: Cat diagnosed with feline saddleback thrombus? Has anyone reading this ever had a cat diagnosed with feline saddleback thrombus? And if so, do any of you know of cats surviving any treatment or surgery?

Answer: The group that may know is the Handicats group on Yahoogroups, those owners have literally seen everything. Sign up over there and ask, any of them who have dealt with this can give you solid information.

Question: What is the difference between thrombus and embolus ? .................

Answer: Thrombus: A fibrinous clot that forms in and obstructs a blood vessel, or that forms in one of the chambers of the heart. (It stays in one place) Embolus: A mass, such as an air bubble, a detached blood clot, or a foreign body, that travels through the bloodstream and lodges so as to obstruct or occlude a blood vessel. (It has broken free and travels)

Question: What is the differences between thrombus and thrombosis?~~?

Answer: Thrombosis: The formation or presence of a blood clot in a blood vessel. The vessel may be any vein or artery as, for example, in a deep vein thrombosis or a coronary (artery) thrombosis. The clot itself is termed a thrombus. If the clot breaks loose and travels through the bloodstream, it is a thromboembolism. Thrombosis, thrombus, and the prefix thrombo- all come from the Greek thrombos meaning a lump or clump, or a curd or clot of milk.

Question: Relationship between heparin and thrombus formation? I know one's a anti-coagulent while the other's a coagulent. But I do not know how the formation is different. Help is appreciated. Thanks in advance.

Answer: A thrombus is a "clot" that forms inside a vessel (where is blood is flowing, at least initially), whereas a "clot" is what forms outside vessles - e.g. on your skin if you cut it. Heparin is a molecule that doctors use to inhibit thrombus (and clot) formation. It binds to one of the natural "clot busters" that the body uses to break down thrombuses (it's called antithrombin III) and enhances its activity.

Question: Query regarding DVT and warfarin. What actually removes existing thrombus? When a person develops DVT (deep vein thrombosis), we put him on heparin/warfarin. However thrombus has already formed. Is the rationale for using warfarin to retard further thrombus formation? Am I right in saying that warfarin actually does not remove any existing thrombus. Removal of thrombus that has already formed, is done by white cells, which happens over next several weeks and months. Is this correct? Thanks

Answer: You are correct. Warfarin will prevent future clots but will not lyse the current clot.

Question: How does an atheroma lead to a thrombus?

Answer: LDL accumulates, macrophages are attracted that try to eat the LDL, the macrophages overeat and die, more macrophages get attracted due to an inflammation response, endothelial cells start to replicate, this thickening of endothelium leads to a narrowing of the blood vessel. The narrowing of the blood vessel can be dangerous when it leads to an obstruction, but it is more dangerous to have an unstable plaque which can tear. This leads to thrombi formation, because a chemical that is called TF (tissue factor) is released from the inner part of the vessel wall that activates coagulation. http://www.physicsforums.com/showthread.…

Question: Multiple Choice Question about a thrombus? A thrombus A. may calcify and result in arteriosclerosis. B. is often associated with high levels of HDLs in the blood. C. may cause hypertension. D. may form at a region of plaque in an artery. Please help. Thank you. Just need the answer.

Answer: D.

Question: Can you invent a mnemonic for distinguishing between: embolism, embolus, thrombosis, and, thrombus?

Answer: what will help me to remember is using the ending of each word example sis,us (ism= in slow moving) and bus

Question: why might a thrombus in a coronary artery cause sudden death?

Answer: 1...the thrombus will lead to the obstruction of the blood flow to the heart itself which in turn cause the ischemia of cardiac muscle and lead to its failure and sudden death 2. a thrombus may give rise to the embolism, and if the emboli gets lodged into any of the vascular Supply of brain wil lead to sudden death due to lack of supply there so the oxygen

Question: should diabetic patient take aspirin to prevent formation of thrombus? please answer if u really know the answer,thank u

Answer: that entirely depends on the cardiologist!! and most advise to take 81mg aspirin tab daily. It also depends on how thick or thin the person's blood is to begin with! Aspirin can cause stomach distress, bleeding ulcers, and other bleeding disorders. Aspirin is not for everyone!!!

Question: why is the metaphysis of a bone a site predisposed to thrombus and later embolus formation?

Answer: this should explain your query http://www.wheelessonline.com/ortho/Hume…

Question: does low shear strees walls of articical hearts contribute thrombus deposition?

Answer: Sounds like it.

Question: how do you distiguish between a thrombus and an embolus?

Answer: A thrombus is simply a blood clot, usually occurring at the site of an injury or ruptured vessel. Sometimes a thrombus will detach itself and move through the blododstream. This is an embolus-a moving blood clot, or thrombus. Hopefully this helps!

Question: my cat has been put to sleep i was told he had saddle thrombus i dont know why it hapened? my oscar went missing for 24 hrs and he goes astray i put flyers out i rang rspca everywere possible,i got a call late at night saying a cat of that description was on the garden across the road from me my husband came running in with him i rang emergency vet i was with him for about an hour and was told the reason his legs were cold an limp was because he had saddle thrombus a blood clot that comes down from the heart,i keep blaming my husband for letting him out,he was a happy cat and rearly loved,it it hadnt been for the lady across the road i wouldnt have had chance to hold him and say goodbye i feel so guilty because i didnt stay with him while he was being put to sleep i was to upset,does anyone know of this illness? and why it came on so quick,he was ok the night he went apart from him not eating his dinner and idnoring me which he never did,peole have said he went off to die but he was only across the road but dont think he had been there long as i went round to every house

Answer: The fact that he got out wouldn't matter at all if he had saddle thrombus.....the heart disease was always there and this could have happened at any time. Sometimes heart disease can be detected at routine vet visits by listening to the heart....but a murmur cannot always be detected. Unfortunetly there was nothing you could to to prevent this. In some cases, if a murmur was heard, and if an echocardiogram was done, medications could have been started, but eventually this would have happened. I'm sorry for your loss. http://www.veterinarypartner.com/Content… -see the part about thromboembolism

Question: What exactly is thrombus? If you know the answer could you please tell me ASAP!? Answer back ASAP

Answer: A clot consisting of fibrin, platelets, red blood cells, and white blood cells that forms in a blood vessel or in a chamber of the heart and can obstruct blood flow. The rupture of atherosclerotic plaques can cause arterial thrombosis (the formation of thrombi), while tissue injury, decreased movement, oral contraceptives, prosthetic heart valves, and various metabolic disorders increase the risk for venous thrombosis. A thrombus in a coronary artery can cause a heart attack